Associations between risk of paralytic ileus and atypical antipsychotic use in mixed dementia

Authors

  • Alexandra Rasuceanu Diaconescu “Carol Davila” University of Medicine and Pharmacy
  • Luiza Spiru “Carol Davila” University of Medicine and Pharmacy

Keywords:

paralytic ileus, antipsychotic use, mixed dementia

Abstract

Dementia affects 35 million people worldwide. Although Alzheimer’s Disease (AD) is the most common form of dementia, 25% of patients have vascular dementia (VaD) and a further 20–40% have mixed dementia with VaD and AD. More than 90% of patients with dementia will experience at least one behavioural and psychological symptoms of dementia (BPSD), such as delusions, hallucinations, agitation and aggression during the course of their condition.  Both atypical and conventional antipsychotics are used in the management of BPSD. However, prescribing trends heavily favour atypical antipsychotics because of a modest advantage with respect to tolerability and safety.

This article wants to present the side effect of atypic antipsychotics in a old female with mixed dementia with behavioural symptoms who developed progressively accentuated transit disorders in the absence of other detectable causes

Author Biographies

Alexandra Rasuceanu Diaconescu, “Carol Davila” University of Medicine and Pharmacy

MD, PhD student

"Carol Davila" University of Medicine and Pharmacy - Bucharest, Romania.

Department of Geriatrics - Gerontology - Elias University Emergency Hospital
(temporary headquarters of the Chronic Disease Hospital “St. Luke’’)

"Ana Aslan" International Foundation- Center for Memory Diseases and Longevity Medicine - Bucharest

Geronto Life Med – Complex Needs Care Home, Bucharest, Romania

Luiza Spiru, “Carol Davila” University of Medicine and Pharmacy

Prof. Dr., MD, PhD

"Carol Davila" University of Medicine and Pharmacy - Bucharest, Romania.

Department of Geriatrics - Gerontology - Elias University Emergency Hospital
(temporary headquarters of the Chronic Disease Hospital “St. Luke’’)

"Ana Aslan" International Foundation- Center for Memory Diseases and Longevity Medicine - Bucharest, 

Published

2022-12-30

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