Archives

  • Brain Aging International Journal, Volume 1, Number 2 (July - December,  2022)

    Brain Aging International Journal
    Vol. 8 No. 2 (2022)

    New series - July - December 2022

  • Brain Aging International Journal - new series Volume 1, Number 1 (January - June, 2022)

    Brain Aging International Journal
    Vol. 8 No. 1 (2022)

    New series (January - June, 2022)

  • OLD SERIES - Brain Aging International Journal - Multilingual Ed.
    Vol. 7 No. 1 (2008)

    Perspectives For a Healthy Brain Aging

    (MULTILINGUAL EDITION: English / Romanian / Greek)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    EDITORIAL
    Hypothesis - driven research and the 'omic' era. Weinstein's synergism.
    Luiza Spiru, Ileana Turcu


    REVIEW
    Rivastigmine in Alzheimer's Disease: Cognitive Function and Quality of Life
    Roberta Annicchiarico, Alessia Federici, Carla Pettinati, Carlo Caltagirone


    ARTICLES
    Mild Cognitive Impairment: Functional Predictors of Progression to Alzheimer’s Disease.
    Michael Borrie, Matthew Smith, Jennie Wells

    Increased 4-Hydroxy-2-Nonenal, a Major End Product of Lipid Peroxidation, in the Brains of two Senescence Accelerated Mouse Strains, SAMP8 and SAMP10
    Xuemin Ye, Jae Il Kim, Harry C. Meeker, Piotr B. Kozlowski, Yong Sun Kim, Richard Rubenstein, Richard I. Carp

    The Histamine H2 receptor Antagonist Cimetidine activates Microglia in APP+PS1 Transgenic Mice
    Megha U. Ambegaonkar, Anand S. Nagle, John C. Breitner, Jason Deleon, Jennifer Alamed, Nedda Wilson, Dave Morgan, Marcia N. Gordon

    Electron Transport Chain Complex II-III Activity is Decreased in Alzheimer's Disease Skeletal Muscle.
    Rolf Wibom, Tor Ansved, Ulla Hamberg, Mari Blomberg, Kristian Borg, Hans Basun, Ulrica von Döbeln, Anita Garlind

    Standardized Geriatric Evaluation in a Group of Patients with Thyroid Pathology and Dementia of Alzheimer's Type.
    Ioana Ioancio, Luiza Spiru, Ion Gheorghe Totoianu, Alexandru Ioancio, Daniela Mitrache

    Görel Bråne Scale (GBS)

    How to activate your brain
    V. Bragin

    Supported human autonomy for recovery and enhancement of cognitive and motor abilities using
    information technologies - SHARE-it 

    Co-morbidities as a Hot Topic in Predementia Conditions. A Romanian Neuroepidemiological Study

    International Conference on Alzheimer’s Disease - ICAD, Chicago, July 2008

  • OLD SERIES - Brain Aging International Journal - Romanian Ed.
    Vol. 6 No. 1 (2007)

    Perspectives For a Healthy Brain Aging

    Published: 2007
    (ROMANIAN EDITION)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    ARTICOLE ORIGINALE
    Eficacitatea rivastigminei la pacienții cu boală Alzheimer severă: un studiu pilot dublu-orb, randomizat
    López-Pousa S., Vilalta-Franch J., Hernandez B., Rapatz G.

    Activitatea complexului enzimatic II-III al lanțului transportor de electroni este scăzută în mușchiul striat al pacienților cu boala Alzheimer 
    Rolf Wibom, Tor Ansved, Ulla Hamberg, Mari Blomberg, Kristian Borg, Hans Basun, Ulrica von Döbeln, Anita Garlind

    Bolile cerebrovasculare stau la baza depresiei pacienților cu afecțiuni neurodegenerative? 
    Carmelle Peisah, Jillian J. Kril, Ian Hickie

    Semnalizarea APP-mediată - noi aspecte 
    Klaus Heese, Takashi Yamada, Yasuo Nagai, Tohru Sawada

    Utilizarea informațiilor obținute de la aparținători în diagnosticul demenței incipiente 
    Anne Rita Oksengraad, A. Braekhus, K. Engedal, K. Laake

    Relația între factorii de risc vascular și caracteristicile plăcilor de aterom carotidiene la pacienții vârstnici 
    Milita Crisby, Jan Nilsson

    Prezentare de caz. Tiroidită atrofică autoimună la o pacientă cu demență vasculară
    Ioana Ioancio, Luiza Spiru, I. Gh. Totoianu

    SCALE DE DIAGNOSTIC:
    NPI (Neuropsychiatric Inventory) 

    PRESS REVIEW
    K4CARE: eServicii de îngrijire la domiciliu bazate pe cunoaștere, într-o Europă în curs de îmbătrânire 
    SHARE-it  - Autonomie Umană Asistată în Vederea Recuperării și Îmbunătățirii Capacităților Cognitive și Motorii cu Ajutorul Tehnologiilor Informaționale 
    Tehnologiile Asistive vor face viața mai ușoară - Proiectul European SHARE-it dezvoltă Tehnologii Asistive pentru Cetățenii Vârstnici ai Europei

  • OLD SERIES - Brain Aging International Journal - Romanian Ed.
    Vol. 5 No. 1 (2005)

    Perspectives For a Healthy Brain Aging

    Published: 2005-03-30
    (DOUBLE ISSUE - ROMANIAN EDITION)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    THE SECOND INTERNATIONAL CONFERENCE OF BRAIN AGING

    Articole originale
    Eficacitatea rivastigminei la pacienții cu boală Alzheimer severă: un studiu pilot dublu-orb, randomizat
    López-Pousa S., Vilalta-Franch J., Hernandez B., Rapatz G.

    Activitatea complexului enzimatic II-III al lanțului transportor de electroni este scăzută în mușchiul striat al pacienților cu boala Alzheimer 
    Rolf Wibom, Tor Ansved, Ulla Hamberg, Mari Blomberg, Kristian Borg, Hans Basun, Ulrica von Döbeln, Anita Garlind

    Bolile cerebrovasculare stau la baza depresiei pacienților cu afecțiuni neurodegenerative? 
    Carmelle Peisah, Jillian J. Kril, Ian Hickie

    Semnalizarea APP-mediată - noi aspecte 
    Klaus Heese, Takashi Yamada, Yasuo Nagai, Tohru Sawada

    Utilizarea informațiilor obținute de la aparținători în diagnosticul demenței incipiente 
    Anne Rita Oksengraad, A. Braekhus, K. Engedal, K. Laake

    Relația între factorii de risc vascular și caracteristicile plăcilor de aterom carotidiene la pacienții vârstnici 
    Milita Crisby, Jan Nilsson

    Prezentare de caz. Tiroidită atrofică autoimună la o pacientă cu demență vasculară
    Ioana Ioancio, Luiza Spiru, I. Gh. Totoianu

    Imagistică. Prezentare de caz. Multiple mici hemoragii în emisferele cerebrale 
    Paul Pătrașcu

    “Ana Aslan” International Academy of Aging

    Scale de diagnostic: Severe Impairment Battery (SIB)
    Anders Wimo, Bengt Winblad

  • OLD SERIES - Brain Aging International Journal - Romanian Ed.
    Vol. 4 No. 4 (2004)

    Perspectives For a Healthy Brain Aging

    Published: 2004-09-30
    (DOUBLE ISSUE - ROMANIAN EDITION)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    THE SECOND INTERNATIONAL CONFERENCE OF BRAIN AGING

    Articole originale
    Cimetidina, antagonist al receptorului histaminic H2, activează microgliile la șoarecii transgenici APP+PS1
    Megha U. Ambegaonkar, Anand S. Nagle, John C. Breitner, Jason Deleon, Jennifer Alamed, Nedda Wilson, Dave Morgan, Marcia N. Gordon

    Profile ale exprimării citokinelor și beta amiloidului în salivă, markeri recunoscuți pentru boala Alzheimer probabilă 
    Paolo Prolo, Francesco Chiappelli, Scott Richard Harper, Negoita Neagos, Milan Fiala, Enzo Grasso, Fiorella Mondino, Maria Gabriella Rosso, Fausto Fanto, Rosa Gabriella Masera, Maria Luisa Sartori, Andrea Dovio, Alberto Angeli

    Creșterea 4-hidroxi-2-nonenal, un produs final important al peroxidării lipidelor, în creierul a două linii murine cu îmbătrânire accelerată, SAMP8 și SAMP10 
    Xuemin Ye, Jae Il Kim, Harry C. Meeker, Piotr B. Kozlowski, Yong Sun Kim, Richard Rubenstein, Richard I. Carp

    Recenzii
    Deficitul cognitiv lejer: predictorii funcționali pentru progresia spre boală Alzheimer 
    Michael Borrie, Matthew Smith, Jennie Wells

    Elemente distinctive și strategii terapeutice pentru demențele asociate parkinsonismului 
    Sally Elizabeth Bashford, Adrian Wilson

    Intervenții non-farmacologice pentru pacienții cu demență și îngrijitorii acestora 
    Magda Tsolaki

    Imagistic`ă. Prezentare de caz: Aspecte RMN în boala Wilson 
    George Iana, Adina Ioana Chiriță, Silviu Mănescu

    Scale de diagnostic: Utilizarea resurselor în demență: RUD Lite
    Anders Wimo, Bengt Winblad

  • OLD SERIES - Brain Aging International Journal
    Vol. 4 No. 3 (2004)

    Perspectives For a Healthy Brain Aging

    Published: 2004-04-30
    (March - April 2004)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    THE SECOND INTERNATIONAL CONFERENCE OF BRAIN AGING 

    REVIEWS
    Discriminators of, and Treatment Strategies for, the Dementias of Parkinsonism
    Sally Elizabeth Bashford, Adrian Wilson

    Increased 4-Hydroxy-2-Nonenal, a Major End Product of Lipid Peroxidation, in the Brains of two Senescence Accelerated Mouse Strains, SAMP8 and SAMP10 
    Xuemin Ye, Jae Il Kim, Harry C. Meeker, Piotr B. Kozlowski, Yong Sun Kim, Richard Rubenstein, Richard I. Carp

    Mild Cognitive Impairment: Functional Predictors of Progression to Alzheimer Disease
    Michael Borrie, Matthew Smith, Jennie Wells


    ARTICLES
    Efficacy of Rivastigmine in Patients with Severe Alzheimer’s Disease: A Double-Blind, Randomized Pilot Study 
    López-Pousa S., Vilalta-Franch J., Hernandez B., Rapatz G.

    The Histamine H2 receptor Antagonist Cimetidine Activates Microglia in APP+PS1 Transgenic Mice 
    Megha U. Ambegaonkar, Anand S. Nagle, John C. Breitner, Jason Deleon, Jennifer Alamed, Nedda Wilson, Dave Morgan, Marcia N. Gordon

    Electron Transport Chain Complex II-III Activity is Decreased in Alzheimer’s Disease Skeletal Muscle 
    Rolf Wibom, Tor Ansved, Ulla Hamberg, Mari Blomberg, Kristian Borg, Hans Basun, Ulrica von Döbeln, Anita Garlind

  • OLD SERIES - Brain Aging International Journal - Romanian Ed.
    Vol. 4 No. 2 (2004)

    Perspectives For a Healthy Brain Aging

    Published: 2004-03-31
    (March 2004)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    Editorial: Modificările stilului de viață la hipertensivii vârstnici 
    Ioan Romoșan, Luiza Spiru, C. Dașcău

    Recenzii
    Cortexul cerebral și senescența - corelații structurale și funcționale (RO)
    A. C. Cuello, A. Ribeiro-da-Silva, Y. De Koninck, M. A. Bruno

    Boala Alzheimer: o tauopatie reală alimentată de disfuncția APP (RO)
    Nicolas Sergeant, André Delacourte

    Efectele fenotipice ale genotipului apoE la șoarecii transgenici (RO)
    G. Ophir, O. Levi, G. Yacovlev, D.M. Michaelson

    Scale de evaluare: Scorul IADL al activităților curente (RO)

    Prezentare de caz: Exercițiile fizice (de rezistență) pot ameliora funcția cognitivă și motorie la un pacient vârstnic cu demență? (RO)
    Vince S. Thomas, Janis B. Petzel

    The 9th International Conference on Alzheimer’s Disease and Related Disorders

    Articole originale
    Tratamentul cu memantin la trei pacienți cu boală Parkinson cu diskinezie și declin cognitiv (RO)
    J. Lökk, B. Winblad

    Plombele dentare de amalgam și relația cu concentrația mercurului în sânge și funcția cognitivă într-o populație urbană vârstnică (RO)
    Nina Johansson, Hans Basun, Poul Holm-Pedersen, Bengt Winblad, Monica Nordberg

  • OLD SERIES - Brain Aging International Journal
    Vol. 4 No. 1 (2004)

    Perspectives For a Healthy Brain Aging

    Published: 2004-03-31
    (January - March 2004)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    EDITORIAL: 
    Hypertension and Lifestyle Modifications in the Elderly
    Ioan Romoșan, Luiza Spiru, C. Dașcău


    REVIEWS: 
    Structural and Functional Correlates in the Aging of the Cerebral Cortex
    A.C, Cuello, A. Ripero-da-Siva, Y. De Koninck, M.A. Bruno

    Alzheimer's Disease: a TrueTauopathy Fueled by APP Disfunction
    Nicolas Sergeant, André Delacourte

    The Phenotypic Effects of the apoE Genotype in Transgenic Mice
    G. Ophir, O. Levi, G. Yacovlev, Michaelson


    ARTICLES
    Mernantine Treatment of three Parkinsonian Patients Having Dyskinesia and Cognitive Decline
    J. Lokk, B. Winblad

    Prevalence of Co-Morbidities in Mild Cognitive Impairment (MCI) Patients
    Luiza Spiru, Florina Cristescu, Raluca Dudău, Paul Pătrașcu

    Dental Amalgam Fillings in Relation to Mercury Concentration in Blood and Cognitive Function in an Elderty Urban Population
    Nina Johansson, Hans Basun, Poul Holm-Pedersen, Bengt Winblad, Monica Nordberg


    CASE REPORT

    Can (Resistance) Exercise Training Improve Cognitive and Physical Function in an Eklerly Patient 
    Vince S. Thomas, Janes B. Petzel

    THE 9TH INTERNATIONAL CONFERENCE ON ALZHEIMER’S DISEASE AND RELATED DISORDERS

  • OLD SERIES - Brain Aging International Journal - Romanian Ed.
    Vol. 3 No. 6 (2003)

    Perspectives For a Healthy Brain Aging

    Published: 2003-12-31
    (November - December 2003)

    Editor in chief: 
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    EDITORIAL
    Îmbătrânirea celulară și consecințele acesteia în nefrologie (RO)

    REVIEW
    Inflamația în boala Alzheimer: rolul său și o posibilă oportunitate terapeutică(RO)
    Gary L. Wenk

    Prevalența comorbidităților la pacienții cu deficit cognitiv lejer (MCI)  (RO)
    Luiza Spiru, Florina Cristescu, Raluca Dudău, Paul Pătrașcu

    Scale de diagnostic. Scorul activităților vieții cotidiene (RO)
    “Ana Aslan” International Academy of Aging

    Imagistică: Tumoră de fosă cerebrală posterioară asociată cu alte leziuni intracraniene  (RO)
    Paul Pătrașcu

    Articole originale
    Profile de expresie genică în hipocamp la șoarecii bătrâni cu și fără tulburări de memorie (RO)
    Jonathan Brouillette, James O'Donnell, Oscar Díaz-Ruiz, Roger Godbout, Rémi Quirion

    Endarterectomia carotidiană la pacienții vârstnici(RO)
    I. A. Szucsik, Luiza Spiru, Ș. I. Drăgulescu, I. Romoșan, Mioara Cocora, M. Gaspar, C. Dina, D. Maximov, Daniela Maximov

    Strategii pentru memorie și limbaj și efectele acestora asupra abilităților cognitive în primele stadii de boală Alzheimer probabilă  (RO)
    Tsantali E., Efklides A., Tsolaki M., Kiosseoglou G.

    The 9th International Conference on Alzheimer’s Disease and Related Disorders

  • OLD SERIES - Brain Aging International Journal - Romanian Ed.
    Vol. 3 No. 5 (2003)

    Perspectives For a Healthy Brain Aging

    Published: 2003-10-31
    (September - October 2003)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    EDITORIAL
    Observații concluzive despre îmbătrânire și senescență (RO)

    Eficiența și siguranța rivastigminei la pacienții cu boală Alzheimer probabilă ușoarã sau moderată în cadru comunitar (RO)
    A Tzimos, I Pittas, A Kazis, M Tsolaki, E Kapaki, G Sgouropoulos, K Karageorgiou, V Kontogianni, A Visviki, T Papapetropoulos, Ch. Paschalis, I Metallinos, I Mylonas, G Mentenopoulos, S Bostanzopoulou, Z Katsarou, A Plaitakis, G Klados, S Balogiannis, V Kosta, A Papadimitriou, A Aspiotis, G Giasakis, A Voulgari, M Dalakas

    Markeri biochimici ai bolii Alzheimer în lichidul cefalorahidian: proteinele tau, tau hiperfosforilat și amiloidul beta (RO)
    Niels Andreasen

    Succesul terapeutic în Boala Alzheimer: inițierea precoce a tratamentului și continuarea lui pe termen lung (RO)
    Carina Manda

    Strategii de tratament în degenerescența lobară frontotemporală (RO)
    Christian Andersen, Per Östberg, Lars-Olof Wahlund, Bengt Winblad

    Eficacitatea și tolerabilitatea memantinului la pacienții cu demență de tip Alzheimer moderat-severã și severă (RO)

    Hemoragie spontană intracerebeloasă (RO)
    Paul Pătrașcu, George Iana

    Testul MMSE (Mini Mental State Examination) și testul orologiului (RO)

  • OLD SERIES - Brain Aging International Journal
    Vol. 3 No. 4 (2003)

    Perspectives For a Healthy Brain Aging

    Published: 2003-08-31
    (July – August 2003)

    Editor in chief: 
    Bengt Winblad


    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    EDITORIAL

    Cell Senescence and its Consequences in Nephrology
    Ioan Romoșan, Luiza Spiru


    REVIEWS

    Non-Pharmacological Interventions for Patients with Dementia and their Caregivers
    Magda Tsolaki

    Inflammation in Alzheimers’s Disease: its Role and an Opportunity for Therapy
    Gary L. Wenk


    ARTICLES

    Hippocampal Gene Expression Profiles in Memory-Impaired and Memory-Unimpaired Aged Rats
    Jonathan Brouillette, James O'Donnell, Oscar Díaz-Ruiz, Roger Godbout, Rémi Quirion

    Development of mtDNA-Transfused Cell Model of Alzheimer’s Disease and Application in Pharmacological Study on Chinese Herb Components
    Zhang Lan, Liu Fang, Jia Jian-Ping, Li Lin

    Memory and Language Strategies and their Effects on the Cognitive Abilities in the First Stages of Probable Alzheimer’s Disease
    Tsantali, E., Efklides, A., Tsolaki, M., Kiosseoglou, G.

    Carotid Endarterectomy in Elderly Patients. Surgical Experience in a Hospital-Based Study
    I.A. Szucsik, Luiza Spiru, S.I.Dragulescu, I.Romoșan, Mioara Cocora, M. Gaspar, C. Dina, D. Maximov, Daniela Maximov


    IMAGES – CASE REPORT

    Tumor of Cerebral Posterior Fossa Associalted with other Intracranial Lesions
    Paul Pătrașcu


    THE 9TH INTERNATIONAL CONFERENCE ON ALZHEIMER’S DISEASE AND RELATED DISORDERS.

  • OLD SERIES - Brain Aging International Journal
    Vol. 3 No. 3 (2003)

    Perspectives For a Healthy Brain Aging

    Published: 2003-06-30
    (May – June 2003)

    Editor in chief: 
    Bengt Winblad

    Editors: Luiza Spiru, Khalid Iqbal

     

     

    EDITORIAL

    Why the First International Conference of Brain Aging - An International Journal?

    Welcome to the Academy - The First International Conference of Brain Aging – An International Journal


    REVIEW

    Prevalence of Dementia in Greek Orthodox Monasteries. The Role of Diet Poor in Lipids and Style of Life
    Tsolaki M, Pantazi Ch., Stiliou F., Aminta M., Diudi, P. Karasoulas S., Kazis A., Pollen D.

    Presenilin Proteins and the γ-Secretase Complex Generating β-Amyloid and APP Intracellular Domain
    Anna Bergman and Jan Naslund


    ARTICLES

    Risk Factors for Early Readmission of Alzheimer Patients to an Acute Care Unit
    L Balardy, F Nourashémi, S Andrieu, T. Voisin, P J Ousset, B Vellas

    Efficacy and Safety of Rivastigmine in Patients with Mild to Moderate Probable Alzheimer’s Disease in a Community Setting
    A. Tzimos, I. Pittas, A. Kazis, M. Tsolaki, E. Kapaki, G. Sgouropoulos, K. Karageorgiou, V. Kontogianni, A. Visviki, T. Papapetropoulos, Ch. Paschalis, I. Metallinos, I. Mylonas, G. Mentenopoulos, S. Bostanzopoulou, Z. Katsarou, A. Plaitakis, G. Klados, S. Balogiannis, V.Kosta, A. Papadimitriou, A. Aspiotis, G. Giasakis, A. Voulgari, M. Dalakas

    Vitamin B 12, Folate and Homocysteine in Persons with Cognitive Impairment
    S. Annerbo, RN, M.Sc., B. Lind, MD, J. Lökk, MD, ass. Professor, L-O. Wahlund, M.D, Professor


    IMAGES – CASE REPORT

    Mild Cognitive Impairment with Subcortical Vascular Features: a Case Report  
    Samantha Galluzzi, Cristiana Calvagna, Cristina Geroldi, Orazio Zanetti, Giuliano Binetti and Giovanni B Frisoni

    The 9th International Conference on Alzheimer’s Disease and Related Disorders

  • OLD SERIES - Brain Aging International Journal
    Vol. 3 No. 2 (2003)

    Perspectives For a Healthy Brain Aging

    Published: 2003-04-30 (March – April 2003)

     

    Editor in chief: 
    Bengt Winblad

    Editors: Luiza Spiru, Khalid Iqbal

     


    EDITORIAL

    Remarks on Aging and Senescence

    Welcome to the Academy: The First International Conference of Brain Aging – An International Journal


    ARTICLES

    Detection of mRNA Level and Mutation of Neurofilament in Alzheimer Disease
    Yipeng Wang, Xinwei Zhou, XiaoChuang Wang, Rong Liu, Qun Wang, and Jianzhi Wang

    Activation of p38 Mitogen-activated Protein Kinase in 139A or 22A Scrapie-infected SAMP8, SAMR1, AKR and C57BL Mice
    Xuemin Ye, Harry C. Meeker, Piotr B. Kozlowski and Richard I. Carp

    The Density of Endothelial Cells in Brain Tissue is Influenced by Gender, Age and Concomitant Brain Pathology
    B Berdel, A Koivisto, H Soininen, M Laakso, I Alafuzoff

    Interrater Reliability of the GBS Scale Used by Staff and Caregivers
    Erik Jedenius, Görel Bråne

    A Carer-Based Index for Identifying Early Dementia in the Elderly Living at Home
    AR Oksengaard, A Braekhus, K Engedal, K Laake

    A Novel Mouse Model of Alzheimer’s Disease
    Luo Huanmin, Chen Zisheng

  • OLD SERIES - Brain Aging International Journal
    Vol. 3 No. 1 (2003)

    Perspectives For a Healthy Brain Aging

    Published: 2003-02-28
    (January - February 2003)

    Editor in chief:
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal


    REVIEWS:

    Treatment Strategies in Frontotemporal Lobar Degeneration
    Christian Andersen, Per Östberg, Lars-Olof Wahlund, Bengt Winblad

    Biomarkers for Alzheimer Disease in the Cerebrospinal Fluid: Tau, Hyperphosphorylated Tau and Amyloid Beta Protein
    Niels Andreasen


    ARTICLES

    New Aspects about APP-signaling
    Klaus Heese, Takashi Yamada, Yasuo Nagai, Tohru Sawada

    Does Cerebrovascular Disease Underpin Depression in Patients with Neurodegenerative Disease?
    Carmelle Peisah, Jillian J. Kril, Ian Hickie

    Families’ Experiences Permitting Brain Autopsy for the Oregon Brain Bank in the Context of the Neuropathology Report
    Lissi Hansen, Jeffery A. Kaye, Rebecca Dorn, Herlene D. Benson, Vida Davies, David Clark, Melvyn J. Ball

    Relation between Vascular Risk Factors and Carotid Plaque Cell Composition and Viability in Elderly Patients
    Milita Crisby, Jan Nilsson

    The Use of Informant Data in the Diagnosis of Early Dementia
    Anne Rita Oksengaard, A. Braekhus, K. Engedal, K. Laake

    Evaluation Instruments in Dementia Resource Utilization in Dementia: “RUD Lite©”
    Anders Wimo, Bengt Winblad


    IMAGES

    Spontaneous Intracerebellar Hemorrhage - Case Report
    Paul Patrascu, George Iana


    CLINICAL OVERVIEWS

    Medical Examination of the Elderly Patient
    Mario Impallomeni


    CONFERENCE ANNOUNCEMENT:

    The First International Conference of Brain Aging – An International Journal

  • Brain Aging International Journal - old series Volume 2, Number 4

    OLD SERIES - Brain Aging International Journal
    Vol. 2 No. 4 (2002)

    Perspectives For a Healthy Brain Aging

    Published: 2002-12-31 (October – December 2002)

    Editor in chief: 
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    REVIEWS

    Towards Harmonisation of Caregiver Outcome Measures
    Henry Brodaty, Alisa Green, Sube Banerjee, Mary Mittelman, Richard Schulz, Peter Whitehouse, Richard Harvey, Mervyn Powell, Martin Prince, Della Rios, Steve Zarit

    The Role of Cognitive Stimulation in Diagnosing Mild-Cognitive-Impairment Subjects at Risk for Alzheimer-Type Dementia
    Inge Cantegreil-Kallen, Jocelyne de Rotrou, Annie Gosselin, Emilie Wenisch, Anne-Sophie Rigaud

    Treatment Strategies in Alzheimer’s Disease
    Vesna Jelic, Bengt Winblad

    ARTICLES

    Early Events of Alzheimer-Like Neurodegeneration in Anti-Nerve Growth Factor Transgenic Mice
    Simona Capsoni, Sabina Giannotta, Antonino Cattaneo

    CGI-94 Controls Neuronal Survival
    Klaus Heese, Takashi Yamada, Yasuo Nagai, Tohru Sawada

    Quetiapine Effectively Reduces Psychotic Symptoms in Patients with Lewy Body Dementia: an Advantage of the Unique Pharmacological Profile?
    Paul Davis and Andrius Baskys

    Major Fluctuations as the Principal Cause of Impairment in Daily Living Activities in a Case of Probable Lewy Body Dementia
    Patricia Marique, Vinciane Wojtasik, Stéphane Adam, Sophie Bechet, Frédéric Roelands, Robert Poirrier, Gustave Moonen, Eric Salmon

    Diagnostic Work-up of Dementia – a Survey among Norwegian General Practitioners
    Anne Brækhus, Knut Engedal

    Further Evidence in Support of the Presence of Behavioral Syndromes in Alzheimer’s Disease
    Roberta Riello, Cristina Geroldi, Orazio Zanetti, Giovanni B. Frisoni

  • Brain Aging International Journal - old series Volume 2, Number 3

    OLD SERIES - Brain Aging International Journal
    Vol. 2 No. 3 (2002)

    Perspectives For a Healthy Brain Aging

    Published: 2002-09-30 (July – September 2002)

    Editor in chief: 
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    REVIEWS

    Treatment Strategies in Alzheimer’s Disease
    Vesna Jelic, Bengt Winblad

    Long-term Efficacy of Cholinesterase Inhibitors
    Serge Gauthier

    Culture and Dementia
    Adesola Ogunniyi, Kathleen S Hall, Olusegun Baiyewu, Oyewusi Gureje, Hugh C. Hendrie

     

    ARTICLES

    Characterizing Rat p18 Amyloid Beta (Aβ) Responsive Protein p18AβrP
    Klaus Heese, Yasuo Nagai, Tohru Sawada

    Plasma Lipids in Patients Newly Diagnosed With Probable Alzheimer’s Disease
    Annica Algotsson, Bengt Winblad

    Calcium/Calmodulin Dependent Protein Kinase II în Alzheimer’s Disease
    Maria Nordlinder, Wen-Lin An, Irina Alafuzoff, Nenad Bogdanovic, Jin-Jing Pei

    Pupil Dilation Test for Alzheimer’s Disease
    Zhiqing Xiang, Yuemin Chen, Wenwei Yan

    Carboxyl-Terminal Fragments of the Amyloid Precursor Protein in Alzheimer’s Disease Brain: Detection of γ-Secretase Products
    Geneviève Evin, R. M. Damian Holsinger, Simone Eggert, Andreas Weidemann, Louise Canterford, David Hoke, Sam Gandy, Catriona McLean, Konrad Beyreuther, Colin L. Masters

    Galantamine Significantly Improves All Aspects of Cognition in Patients With Advanced-Moderate Alzheimer’s Disease
    R. Blesa, S. Schwalen

  • OLD SERIES - Brain Aging International Journal
    Vol. 2 No. 2 (2002)

    Perspectives For a Healthy Brain Aging

    Published: 2002-06-31 (April - June 2002)

    Editor in chief: 
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

     

    EDITORIAL: 
    Aging Policies - Luiza Spiru & Bengt Winblad

     

    REVIEW

    G-Protein Regulation of Signal Transduction in Alzheimer’s
    Angela García-Jiménez, Johan Fastbom, Bengt Winblad, Richard F. Cowburn

    Tauopathy Upstream of the Amyloid Cascade in Alzheimer’s Disease
    Delacourte André, Sergeant Nicolas, Buée Luc

     

    ARTICLES

    Regional and Cellular Distribution of Synaptic Proteins în the Normal Human Brain
    Nenad Bogdanovic, Pia Davidsson, Johan Gottfries, Inga Volkman, Bengt Winblad, Kaj Blennow

    Well-Being in Nonagenarians and the Impact of Objective Health
    Pernilla Hillerås, Hedda Agüero-Torres, Anthony. F. Jorm, Margareta Westerbotn, Bengt Winblad

    Dementia Screening in General Practice: Optimised Scoring for the Clock Drawing Test
    Beat Thalmann, René Spiegel, Hannes B. Stähelin, Dorothee Brubacher, Doris Ermini-Fünfschilling, Stefan Bläsi, Andreas U. Monsch

    A Multifaceted Approach to Cognitive Decline in Patients with Alzheimer’s Disease
    Robert L. Bender, Ray Moore, Dan Russell, Yogesh Shah, Kathy Davidson, Dave Michael

    Cognitive Stimulation: A New Approach for Alzheimer’s Disease Management
    Jocelyne de Rotrou, Inge Cantegreil-Kallen, Annie Gosselin, Emily Wenisch, Anne-Sophie Rigaud

     

    IMAGES

    Voxel-Based Morphometry in Multiple System Atrophy
    Samantha Galluzzi, Cristina Testa, Francesca Sabattoli, Cristina Geroldi, Alberto Beltramello, Giovanni B. Frisoni

    CT and MRI Aspects of the Aging Brain
    Adina I. Chiriță, Andreea Marinescu, Rareș Nechifor, George Iana

     

    CLINICAL OVERVIEW

    Common Pitfalls in the Diagnosis of Disease in the Elderly
    Dr. M. Impallomeni, MD, FRCP

     

    EXPERIENCE

    Peripheral Nerve Microsurgery – Romanian Experience
    Doina Dumitrescu-Ionescu, PhD, MD

    THOUGHTS, OTHER THAN DOCTORS’
    How Are You?
    Magda Cuturicu

    News

  • OLD SERIES - Brain Aging International Journal
    Vol. 2 No. 1 (2002)

    Perspectives For a Healthy Brain Aging

    Published: 2002-03-31 (January - March 2002)

    Editor in chief: 
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal



    EDITORIAL: 
    Alzheimer’s disease
    Bengt Windblad, Luiza Spiru, Khalid Iqbal

    The Nobel Prize in Physiology or Medicine 2001
    Nobel Prize Centennial 1901–2001

    Thoughts from outside the antiseptic environment:
    Beyond Definitions and Stereotypes 
    Magda Cuturicu

    REVIEW
    Pathophysiology of Frontotemporal Dementia - Cytoskeleton Abnormalities and Autoimmunity? 
    Magnus Sjögren

    ARTICLES
    The Stress-Activated C-jun Amino-Terminal Kinase (JNK) in Alzheimer's Disease Neurofibrillary Degeneration 
    Jin-Jing Pei, Wen-Lin An

    Alterations of Nitric Oxide Synthase Expression and Activity in Alzheimer's Disease Brains 
    Andrew Law, Wen-Hua Zheng, Serge Gauthier, Rémi Quirion

    Predicting Progression to Dementia in a Memory Clinic Population: Clinical Indicators Are of Limited Value
    G.K. Wilcock, A.O. Hughes, A. Jordan, S. H. MacGowan

    Cognitive Compensation Can Overcome Age-Associated Physiological Losses in Processing Odors, Pictures, and Flavors
    Robert J.F. Elsner

    IMAGES
    MRI of Wilson’s Disease 
    George Iana, Adina Ioana Chirita, Silviu Manescu

    Right Cerebellar Hemorrhage 
    Paul Pătrașcu

    Multiple Small Hemorrhages in the Cerebral Hemispheres
    Paul Pătrașcu

  • OLD SERIES - Brain Aging International Journal
    Vol. 1 No. 1 (2001)

    Perspectives For a Healthy Brain Aging

    Published: 2001-12-31 (October - December 2002)

    Editor in chief: 
    Bengt Winblad

    Editors:
    Luiza Spiru, Khalid Iqbal

     

    EDITORIAL: 
    [E1] A Bridge between Brain and Aging Research
    Bengt Winblad
    [E2] Controlling and Overcoming Brain Aging
    Luiza Spiru
    [E3] Importance of Brain Aging
    Khalid Iqbal

    REVIEW:
    [R1] Use and Limitations of Olfactory Tests in Diagnosis of Alzheimer’s Disease
    Robert J.F. Elsner

    [R2] Are Intracellular Paired Helical Filaments (PHFs) from Alzheimer’s Disease Toxic for a Neuron?
    Félix Hernández, Mar Pérez, José J. Lucas, Jesús Avila

    ARTICLES
    [A1] Effects of Hospitalisation on Cognitive Function, Activities of Daily Living Capacity and Behaviour in Alzheimer’s Disease Patients: a Longitudinal Study
    Luiza Spiru, Pierre-Jean Ousset, Bruno Vellas

    [A2] Interleukin-1α Gene Polymorphism Influences the Severity of Neurodegeneration in Alzheimer’s Disease
    M. Overmyer, M. Pirskanen, M. Hiltunen, S. Helisalmi, A.M. Koivisto, H. Soininen, I. Alafuzoff

    [A3] The Biochemical Spreading of Tau and Amyloid β - Precursor Protein Pathologies in Aging and Sporadic Alzheimer’s Disease
    André Delacourte, Nicolas Sergeant, Danie Champain, Annick Wattez, Claude-Alain Maurage, Florence Lebert, Florence Pasquier, Jean-Philippe David

    [A4] Visuo-Constructional Ability: a Solitary Brain Process or Part of a Complex System?
    Magda Tsolaki, John Tarnanas, Stefanos Brilakis, Kostas Fountoulakis, Kostantina Griva, Aristides Kazis

    [A5] Effect of Training on Tau Phosphorylation in Rat Brain
    Yipeng Wang, Xiaomei Liao, Zefen Wang, Shijie Liu, Jianzhi Wang